Haloxyl®, also known as Palmitoyl Tetrapeptide-7, reduces puffiness and dark circles under the eyes. This peptide works by encouraging proper circulation in that area. Essentially, studies have proven that Haloxyl® reverses the fluid build up that naturally occurs when you sleep. Eyelid swelling is a common cause of puffiness and dark circles. Accordingly, when you lie down, gravity causes fluid to accumulate in your lower eyelids. Haloxyl® counteracts this effect by increasing the lymphatic drainage by 85% in clinical studies. Furthermore, a recent clinical study by SeDerma® concluded that Haloxyl® reduces dark circles under the eyes by 600%. This is the result of the proprietory way that Haloxyl® breaks down and flushes out of the eye area the toxin-formed pigmented blood that causes these dark circles to form. 22 healthy subjects applied a moderate 2% concentration of Haloxyl® for 8 weeks, and received a 19% reduction in the dark colored circles under the eyes.

The components of Eyeliss™ are as follows;

	Hesperidin methyl chalcone acts to decrease the capillary permeability of the sensitive skin of the lower eylid. This newly discovered molecule works fast to prime the delicate skin for lymphatic drainage and toning.
	Dipeptide Valyl-Tryptophane is a peptide who's purpose is to increase lympatic circulation leading to drainage. It is this peptide which is most responsible for safely draining the fluid out of the puffy eye bags.
	Lipopeptide Pal-GQPR acts quickly to improve skin firmness and elasticity, whereby removing fine lines and wrinkles on the sensitive lower eyelid skin. Furthermore, this peptide actively decreases the inflammatory phenomena commonly caused by other lymphatic drainage agents.

Principle of a 3D morphometric study

The software measures the distance between the surface of the bag before treatment and the surface of the bag after treatment

Matrikines are messengers of cutaneous restructuration and repair. They activate the neosynthesis of extracellular matrix macromecules, thus providing Matrixyl™3000 with a visible anti-wrinkle efficacy. As messenger molecules, these matrikines™ are capable of regulating cell activities. More specifically, they interact with specific receptors to trigger the stimulation of certain genes involved in the process of extracellular matrix renewal and cell proliferation.

With age these complex mechanisms become progressively weaker. As such, the supplemental use of an advanced restoration multi-peptide like Matrixyl™3000 becomes an essential part of the formula for maintaining smooth skin around the eyes. Accordingly, in extensive clinical testing undertaken by SeDerma, the application of a serum containing Matrixyl™3000 has been proven to reduce unwanted expression wrinkles by 45% in only 2 months, along major and significant improvements in elasticity and tone.

Inyline™ Solution, created by Lipotec, brings a novel approach to the cosmetic treatment of expression wrinkles around the eyes. There are two main strategies to minimise muscle contraction: PRE-SYNAPTIC strategy, which involves different mechanisms that restrain or inhibit the release of the neurotransmitter (acetylcholine) from the motor neuron. The most known example of this is a cosmetic injection, which inhibits ACh release into the synapse from the vesicles in such a dramatic way that it paralyses the muscle. POST-SYNAPTIC strategy, which avoids or diminishes the ligand (ACh) – receptor (AChR) binding responsible for the formation of the action potential. In this strategy, although the neurotransmitter is released into the synapse, the post-synaptic apparatus does not respond to it. Inyline™ targets this second strategy by blocking the agrin binding site in MuSK and its mechanism of action causing modulation of muscle contraction leading to muscle relaxation. In the treatment of expression wrinkles around the eyes, its pathway is critical in the contraction process and therefore its blockage results in muscle relaxation, with the skin surface appearing smoother and line depth decreasing.

As a molecule able to activeate TGF, SYN®-COLL is considered to be an ideal aqueous based peptide. It contains a unique sequence designed to mimic the human body's own mechanism to product collagen via TGF. Accordingly, SYN®-COLL actively compensates for any collagen deficit, thus making the skin look younger.

Anti-wrinkle effect of SYN®-Coll.

The study was performed on 60 volunteers. SYN®-COLL has been compared against placebo and against a reference substance.

Both products have been used at the recommended use level calculated for their active principle. The study lasted 84 days with a twice- daily application

Anti-wrinkle effect of SYN®-Coll.

Using the PRIMOS® technique, parallel stripe patterns are projected on the sample with successive phase shift. The analysis of fringe deformations provided a qualitative, as well as quantitative, evaluation of each height profile.

Macrophotographs

Macro photographs are done with Nikon® D1 a digital camera.
The photographs are taken in standardized, indirect light.

After 84 days of twice-daily application of 2.5% SYN®-COLL parameters average relief (Rz) and maximum relief (Rt) significantly decreased by -12%: -22 μm and -36 μm respectively (p= 0.05) characterizing smoothing and anti wrinkle effects.

Elite Serum™ Rx is Oil-Free and Moisturizes like an Eye Cream

In addition, studies have shown that natural seaweed extracts inhibit elastase and collagen, two enzymes linked to the break down of the structural proteins found in the skin. As the in vivo tests also demonstrated, it is able to inhibit a range of viruses entering cells, and as such it is the ideal ingredient for therapeutic facial cleanser.

Improves skin appearance

In-vivo tests revealed the ingredient to be effective in reducing skin aging among clinical trial panelists. Subjects applied a formulation that included seaweed extract at one per cent twice a day for 12 weeks, which resulted in a 9.45 per cent decrease in wrinkle depth. Expert grading carried out at the end of the study showed skin tone, firmness, and elasticity, showed an improvement of 67.6 per cent. Similarly, overall skin appearance improved 68.4 per cent. The expert grading also reported a 92.1 per cent improvement in skin dryness and roughness.

Hyaluronic Acid is the key for maintaining water substances in human skin. Due to aging, natural Hyaluronan concentration in the skin decreases at an alarmingly increasing rate over time. Accordingly, the skins ability to maintain moisture is weakened, and it gives the appearance of being dry and rough. When Hyaluronic Acid is applied back to the skin, it penetrates the dermis, combines with water, and promotes micro circulation and nutrient absorption. It forms an air permeable layer, to keep the skin moist and smooth. The result is a rapid skin rejuvenation, diminishing the appearance of wrinkles, crows feet and other cosmetic signs of age around the eyes caused by sun exposure, smoking, stress, and other common factors Hyaluronic Acid is one of the newest injectable facial treatment gels designed to slow and hide the effects of aging.

This image illustrates the effects of aging on hyaluronic acid content in skin. Notice how the naturally occuring hyaluronic acid content in skin falls dramatically at age 45.

A concentrated dose of ultra-moisturizing Hyaluronic Acid and Seaweed Extract helps to increase skin suppleness and fill delicate fine lines. Concurrently, the potent peptides of Argireline®, Hyloxyl®, Eyeliss™, Matrixyl™3000, SYN®-COLL and SNAP-8 have been shown to revitalize lost collagen and fibronectin in the skin. It is this natural loss of collagen that causes the thinning skin and wrinkling that is normally associated with aging skin.

Elite Serum™ Rx (Extra Strength) contains only the best clinically tested peptides from the likes of Pentapharm, Sederma, Lipotec, LucasMeyer and Centerchem. These companies are at the forefront of the latest in advanced dermatological discoveries. SkinPro® is always one of the first manufacturers to know about new breakthroughs in skin care technology, and an early adopter of its implementation in products.

So, while there are a number of versions of Elite Serum™ that have been produced over the years, this official website sells only the current and most updated formula that reflects the pinnacle of continued research and development. In order to guarantee authenticity and that you are buying the latest and most efficacious version available, SkinPro® highly recommends that you use only Elite Serum™ Rx (Extra Strength). This is available through our secure checkout system.

Formulated with the highest concentration of medical grade ingredients. Rich seaweed extract base as used by the world's most expensive serums. Contains scientifically advanced peptides that have proven results. Delivers a youthful and vibrant appearance around the eyes. Rapidly brings oxygen and nutrients to the eye area. Reduces the appearance of dark circles and puffiness. Diminishes the appearance of fine lines and wrinkles. Feel the difference directly under and around the eye area within minutes. Ultra-lightweight and fast-absorbing application. No injection needed. It works on areas where painful cosmetic injections can not. A Cooling, hyper toning sensation indicates that the serum is working. Scientifically designed as hypoallergenic, non-sensitizing and non-irritating. Can be used safely and beneficially in conjunction with other skin care products. Ability to work alone as needed as a powerful eye serum. Manufactured in the USA in an advanced FDA registered research laboratory.

The award-winning serum is contained in a 0.47 oz applicator syringe. This is enough for a 45-60 day supply when used twice daily, as directed. Elite Serum™ Rx is so powerful, that only a tiny drop needs to be dispensed for maximum effectiveness. The patent-pending syringe that houses the serum is scientifically engineered for easy and even distribution from the pump to your fingertip, cutting out the guesswork normally associated with other serums.

The extra strength blend contains an extremely potent concentration of Argireline®, Hyloxyl®, Eyeliss™, Matrixyl™3000, SYN®-COLL and SNAP-8. This is the only formula on the market designed by scientists that contains this unique combination of advanced and clinically proven peptides that are designed to reviatlize and rejuvenate lost collagen and fibronectin in the skin.

Elite Serum™ Rx (Extra Strength) was scientifically designed and formulated by clinically trained cosmetic pharmacist Irwin Grams. It is manufactured in a state of the art 70,000 square foot facility in Miami, Florida. From the ISO 9002 laboratory to the production staff, all employees are all trained on GMPs, SOPs and all FDA rules and regulations. The facilities are subject to random inspection from the United States Food and Drug Administration, the State of Florida Health Department and the Department of Agriculture.

The development of Elite Serum™ Rx (Extra Strength) combines years of dedicated scientific research and development by a world-class team of cosmetic pharmacists and chemists. Research and development is the most important objective at SkinPro®. Never before has such a single-purpose cosmeceutical been so potent that the most respected cosmetic surgery medical journal in the world, Plastic Surgery Practice, praised its efficacy in an unsolicited editorial. For the first time ever, ordinary skin care consumers can experience and enjoy for themselves the benefits of a needle-free eye serum that works where painful cosmetic injections can not.

Have the numerous medical accolades, the journal and media awards, or the proven skin care science not yet convinced you to give this product a try? If so, you may be waiting to see what actual customers have to say about their experiences with this incredible new anti-aging eye serum. We encourage you to visit our YouTube Channel where real users have submitted review videos of all types. Following your initial evaluation, please consider submitting your genuine video or written review. Or, simply call us toll-free and tell us what you think about Elite Serum™ Rx (Extra Strength).   As always when dealing with SkinPro®, your satisfaction is guaranteed.